This study addresses endosomal escape in oligonucleotide therapies and how engineered peptides can enhance intracellular drug delivery efficiency.

Scientists have long known that cellular membranes vary in thickness, but measuring those differences inside actual cells has been out of reach. Until now, scientists could only measure membrane ...

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear. Research published in the Biophysical Journal shows that ...

Cells may generate their own electrical signals through microscopic membrane motions. Researchers show that active molecular processes can create voltage spikes similar to those used by neurons. These ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. In order to increase the lifetime of polymer electrolyte membrane (PEM) fuel cells ...

The researchers say it was taught in biochemistry class for many decades that glycolysis occurred uniformly in the cytosol, or the fluid matrix of the cell. But when the Johns Hopkins team examined ...

Simple Minds are on their way back to the Bay Area, set to thrill ‘80s music fans with a songbook that includes such gems as “Alive and Kicking,” “Sanctify Yourself,” “Waterfront” and — oh, yeah, — a ...

In this interview, News Medical talks to Patrick D. Sinko about the role of particle size, dose, and confinement parameters in advancing drug absorption modeling. Could you explain what a boundary ...

For the 80 million people worldwide with celiac disease, the only treatment available is to cut grains like pasta and bread out of their lives. But researchers are hoping to change that with a new ...