A new research paper was published in Oncotarget, titled, "Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell ...

SALT LAKE CITY— For the first time, a mutation in HIF2α, a specific group of genes known as transcription factors that is involved in red blood cell production and cell metabolism, has been identified ...

This is an ASCO Meeting Abstract from the 2022 ASCO Genitourinary Cancers Symposium. This abstract does not include a full text component.

The efficacy and adverse event profiles of HIF-PHIs may differ among agents. Although all hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) target the HIF pathway, the individual ...