A peptide bridge is designed to construct a fusion enzyme with electrostatic cofactor channeling, reducing NADPH input by two orders of magnitude or decreasing reaction time threefold with the same ...

The snapshots reveal key reactions steps. At 0 ms, water molecules occupy the substrate-binding site. At 50 ms, a substrate-cofactor intermediate forms. At 100 ms, the product is released, and the ...

This is done by enzymes. Each enzyme is supported by a so-called cofactor, sometimes referred to as a "helper molecule." In a similar way, bacteria can "consume" ethylene glycol, using enzymes and ...

Enzymology is the study of enzymes and enzyme-catalyzed reactions. Enzymes are biological catalysts that accelerate the rate of biological reactions. They can also perform multiple reactions ...